Electron Microscopy (EM & Cryo-EM/ET)
Plasma treatment is used in electron microscopy, including cryo-EM, to clean and modify sample surfaces, enhancing imaging accuracy. By removing organic contaminants and creating a hydrophilic surface, plasma treatment improves the adhesion of samples and reduces charging effects during imaging. In cryo-EM, it aids in the uniform distribution of vitrified ice, ensuring better sample preservation and image quality. Plasma-treated grids enhance sample adherence and reduce beam-induced movement, crucial for obtaining high-resolution images of biological specimens at cryogenic temperatures. Overall, plasma treatment is essential for preparing pristine, stable samples for electron microscopy.
Learn more about how plasma treatment is used for your specific application in the following application notes:
Cryogenic Electron Microscopy (Cryo EM)
Cryogenic electron microscopy (Cryo-EM) has emerged as one of the most powerful tools in structural biology, enabling researchers to resolve protein complexes, receptor-ligand interactions, and viral structures at near-atomic resolution. A critical...