Biology & Biomedical
Effective biological and biomedical research requires specific control of the cellular microenvironment and biomaterial characteristics. Plasma treatment cleans, sterilizes and activates the surfaces of biomaterials through the introduction of functional groups without affecting the bulk. Increased hydrophilicity or hydrophobicity of material surfaces increase the adhesion, coverage and proliferation of cells or induce the formation of spheroids respectively. In addition, plasma treatment has been shown to improve biocompatibility and antibiofouling characteristics for numerous applications. As a result plasma treatments is used extensively for cell seeding, protein adsorption, biomaterial coating and implant surface activation. This page contains brief application summaries and relevant articles concerning the use of plasma treatment in biological and biomedical research.
Titanium Implants
Plasma treatment is used to tailor titanium and titanium alloy surface properties for improved osseointegration in dental and orthopedic implant research. Titanium is a well-known and frequently used implant biomaterial due to its biocompatibility, high corrosion...
Cell Scaffolds
Cell Scaffolds play an integral role in cell studies and tissue engineering by providing structural support and chemical cues vital for cell viability, proliferation and differentiation. In the following post, you will find information regarding cell scaffold...
DNA Combing
DNA Combing, a technique used in the analysis of single molecules of DNA, offers researchers an opportunity to better understand the dynamics of replication, transcription and individual molecule interactions. While advances in DNA sequencing technology have rapidly...
Tissue Culture Plastic (Polystyrene)
Inexpensive, disposable and transparent, plasma treated polystyrene, or tissue culture plastic (TCP), is the most extensively used cell culture material, not only because of its aforementioned qualities but because of its biological affinity....
APTES
(3-Aminopropyl)triethoxysilane (APTES), an aminosilane originally developed as an adsorbent for affinity chromatography, has developed into a versatile tool for improving surface chemistry in cell studies and microfluidic device fabrication....