Biology & Biomedical
Effective biological and biomedical research requires specific control of the cellular microenvironment and biomaterial characteristics. Plasma treatment cleans, sterilizes and activates the surfaces of biomaterials through the introduction of functional groups without affecting the bulk. Increased hydrophilicity or hydrophobicity of material surfaces increase the adhesion, coverage and proliferation of cells or induce the formation of spheroids respectively. In addition, plasma treatment has been shown to improve biocompatibility and antibiofouling characteristics for numerous applications. As a result plasma treatments is used extensively for cell seeding, protein adsorption, biomaterial coating and implant surface activation. This page contains brief application summaries and relevant articles concerning the use of plasma treatment in biological and biomedical research.
Immunoassay Development
Immunoassays identify disease biomarkers in patient samples and enable the detection of viruses, cancers and various other pathogens by exploiting the relationship between antibodies and antigens [1]. Widely used diagnostic immunoassays such as...
Fluorescence Microscopy
Plasma cleaning is essential to the preparation of fluorescence microscopy samples. Plasma removes organic contamination and introduces polar groups to glass or quartz slide surfaces. As a result, plasma removes fluorescent impurities that would...
Organ on a Chip
Organ on a chip models, fabricated with plasma treatment, replicate key tissue structure, function and other physiological characteristics to better explore drug delivery, toxicology and disease progression in vitro. In medical research, in vivo...
Titanium Implants
Plasma treatment is used to tailor titanium and titanium alloy surface properties for improved osseointegration in dental and orthopedic implant research. Titanium is a well-known and frequently used implant biomaterial due to its biocompatibility,...
Cell Scaffolds
Cell Scaffolds play an integral role in cell studies and tissue engineering by providing structural support and chemical cues vital for cell viability, proliferation and differentiation. In the following post, you will find information regarding...