Microfluidic Devices using Rigid Polymers

In addition to PDMS, microfluidic devices are also fabricated from other thermoset or thermoplastic polymers to take advantage of the varying material properties offered by more rigid polymers. Plasma combined with thermal treatment can be applied to bond these polymer surfaces.

Article

Horstman EM, Goyal S, Pawate A, Lee G, Zhang GGZ, Gong Y, and Kenis PJA. "Crystallization Optimization of Pharmaceutical Solid Forms with X-ray Compatible Microfluidic Platforms". Cryst. Growth Des. 2015 15: 1201--1209 10.1021/cg5016065
Zilio C, Sola L, Damin F, Faggioni L, and Chiari M. "Universal hydrophilic coating of thermoplastic polymers currently used in microfluidics". Biomed. Microdevices 2014 16: 107--114 10.1007/s10544-013-9810-8
Borysiak MD, Bielawski KS, Sniadecki NJ, Jenkel CF, Vogt BD, and Posner JD. "Simple replica micromolding of biocompatible styrenic elastomers". Lab Chip 2013 13: 2773--2784 10.1039/c3lc50426c
Chantiwas R, Hupert M, Pullagurla S, Balamurugan S, Tamarit-Lopez J, Park S, Datta P, Goettert J, Cho Y, and Soper S. "Simple replication methods for producing nanoslits in thermoplastics and the transport dynamics of double-stranded DNA through these slits". Lab Chip 2010 10: 3255--3264 10.1039/c0lc00096e
Hu X, He Q, Lu H, and Chen H. "Fabrication of gold microelectrodes on polystyrene sheets by UV-directed electroless plating and its application in electrochemical detection". J. Electroanal. Chem. 2010 638: 21--27 10.1016/j.jelechem.2009.10.026
Mehta G, Lee J, Cha W, Tung YC, Linderman JJ, and Takayama S. "Hard Top Soft Bottom Microfluidic Devices for Cell Culture and Chemical Analysis". Anal. Chem. 2009 81: 3714--3722 10.1021/ac802178u
Hao Z, Chen H, Zhu X, Li J, and Liu C. "Modification of amorphous poly (ethylene terephthalate) surface by UV light and plasma for fabrication of an electrophoresis chip with an integrated gold microelectrode". J. Chromatogr., A 2008 1209: 246--252 10.1016/j.chroma.2008.08.088
Bhattacharyya A, and Klapperich CM. "Mechanical and chemical analysis of plasma and ultraviolet-ozone surface treatments for thermal bonding of polymeric microfluidic devices". Lab Chip 2007 7: 876--882 10.1039/b700442g
Brown L, Koerner T, Horton JH, and Oleschuk RD. "Fabrication and characterization of poly(methylmethacrylate) microfluidic devices bonded using surface modifications and solvents". Lab Chip 2006 6: 66--73 10.1039/b512179e
Kentsch J, Breisch S, and Stezle M. "Low temperature adhesion bonding for BioMEMS". J. Micromech. Microeng. 2006 16: 802--807 10.1088/0960-1317/16/4/017
Kong Y, Chen HW, Wang YR, and Soper SA. "Fabrication of a gold microelectrode for amperometric detection on a polycarbonate ellectrophoresis chip by photodirected electroless plating". Electrophoresis 2006 27: 2940--2950 10.1002/elps.200500750

Harrick Plasma is a leading supplier of plasma equipment to the research community. We have been providing quality tabletop plasma devices specifically designed for laboratory and R&D use for over 30 years.