Surface Enhanced Raman Spectroscopy (SERS) Substrates

Raman signal intensity can be greatly enhanced when probing organic or biological molecules on substrates decorated with metallic nanostructures. Below are users' publications that report using our plasma instruments to fabricate SERS substrates and to remove probe molecules from SERS substrates without compromising the nanostructure morphology.

Article

Tran M, Whale A, and Padalkar S. "Exploring the Efficacy of Platinum and Palladium Nanostructures for Organic Molecule Detection via Raman Spectroscopy". Sensors 2018 18: 147 10.3390/s18010147
Yap LW, Chen H, Gao Y, Petkovic K, Liang Y, Si KJ, Wang H, Tang Z, Zhu Y, and Cheng W. "Bifunctional plasmonic-magnetic particles for an enhanced microfluidic SERS immunoassay". Nanoscale 2017 9: 7822-7829 10.1039/C7NR01511A
Ahn H-J, Thiyagarajan P, Jia L, Kim S-I, Yoon J-C, Thomas EL, and Jang J-H. "An optimal substrate design for SERS: dual-scale diamond-shaped gold nano-structures fabricated via interference lithography". Nanoscale 2013 5: 1836--1842 10.1039/c3nr33498h
Paquet-Mercier F, Aznaveh N, Safdar M, and Greener J. "A Microfluidic Bioreactor with in Situ SERS Imaging for the Study of Controlled Flow Patterns of Biofilm Precursor Materials". Sensors 2013 13: 14714--14727 10.3390/s131114714
Cathcart N, and Kitaev V. "Multifaceted prismatic silver nanoparticles: synthesis by chloride-directed selective growth from thiolate-protected clusters and SERS properties". Nanoscale 2012 4: 6981--6989 10.1039/c2nr32031b
Correia-Ledo D, Gibson KF, Dhawan A, Couture M, Vo-Dinh T, Graham D, and Masson J-F. "Assessing the Location of Surface Plasmons Over Nanotriangle and Nanohole Arrays of Different Size and Periodicity". J. Phys. Chem. C 2012 116: 6884--6892 10.1021/jp3009018
Lu G, Li H, Wu S, Chen P, and Zhang H. "High-density metallic nanogaps fabricated on solid substrates used for surface enhanced Raman scattering". Nanoscale 2012 4: 860 -- 863 10.1039/c1nr10997a
Cathcart N, and Kitaev V. "Monodisperse Hexagonal Silver Nanoprisms: Synthesis via Thiolate-Protected Cluster Precursors and Chiral, Ligand-Imprinted Self-Assembly". ACS Nano 2011 5: 7411--7425 10.1021/nn2023478
Kawaguchi K, Saito M, Takahiro K, Yamamoto S, and Yoshikawa M. "Blueshift and Narrowing of Localized Surface Plasmon Resonance of Silver Nanoparticles Exposed to Plasma". Plasmonics 2011 6: 535--539 10.1007/s11468-011-9233-4
Negri P, Marotta N, Bottomley L, and Dluhy R. "Removal of Surface Contamination and Self-Assembled Monolayers (SAMs) from Silver (Ag) Nanorod Substrates by Plasma Cleaning with Argon". Appl. Spectrosc. 2011 65: 66--74 10.1366/10-06037
Masson J-F, Gibson KF, and Provencher-Girard A. "Surface-Enhanced Raman Spectroscopy Amplification with Film over Etched Nanospheres". J. Phys. Chem. C 2010 114: 22406--22412 10.1021/jp106450y
Camargo P, Cobley C, Rycenga M, and Xia Y. "Measuring the surface-enhanced Raman scattering enhancement factors of hot spots formed between an individual Ag nanowire and a single Ag nanocube". Nanotechnology 2009 20: 434020 10.1088/0957-4484/20/43/434020
Camargo P, Rycenga M, Au L, and Xia Y. "Isolating and Probing the Hot Spot Formed between Two Silver Nanocubes". Angew. Chem. Int. Ed. 2009 48: 2180--2184 10.1002/anie.200806139
Kinnan MK, Kumbhar A, and Chumanov G. "Plasma Reduction of Silver Compounds for Fabrication of Surface-Enhanced Raman Scattering Substrates". Appl. Spectrosc. 2008 62: 721--726 10.1366/000370208784909463
Muniz-Miranda M, Pergolese B, Bigotto A, and Giusti A. "Stable and efficient silver substrates for SERS spectroscopy". J. Colloid Interface Sci. 2007 314: 540--544 10.1016/j.jcis.2007.05.089
Carron K, Mullen K, Lanouette M, and Angersbach H. "Selective-Ultratrace Detection Of Metal-Ions With Sers". Appl. Spectrosc. 1991 45: 420--423 10.1366/0003702914337100

Harrick Plasma is a leading supplier of plasma equipment to the research community. We have been providing quality tabletop plasma devices specifically designed for laboratory and R&D use for over 30 years.