A structure includes a substrate and a first plurality of bilayers on the substrate. The first plurality of bilayers includes a first alyer including an antimicrobial peptide having a charge, and a second layer including a polyelectrolyte having a charge opposite the charge of the first layer. At least a portion of the structure is capable of degrading by sequential removal of the first layer and the second layer, and releasing the antimicrobial peptide from the structure.
Chuang, H. F., A. Shukla, C. R. Loose, P. T. Hammond-Cunningham, G. Stephanopoulos
Massachusetts Institute of Technology
US 20090258045 A1