HARRICK PLASMA

Micro-Fluidic Device for Measuring Osmotic Second Virial Coefficients

A micro-fluidic device having a cavity containing a solid support (e.g., a plurality of particles) and a biomolecule immobilized on a surface of the solid support is provided. The micro-fluidic device can be used to monitor interactions between a biomolecule immobilized on the solid support. For example, the micro-fluidic device can be used to monitor protein self-interactions wherein the protein in the sample is the same protein as that immobilized on the surface of the solid support. A method of making the micro-fluidic device is also described. The micro-fluidic device can be used for chromatographic applications where sample consumption is crucial.

Wilson, Wilbur W., Charles S. Henry, Carlos D. Garcia

Mississippi State University

US6974678 B2

2005-12-13

2004-04-08

2007-03-07

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