HARRICK PLASMA

Molecular Level Interactions Between Blood Components and Model Biomaterials Studied by Atomic Force Microscopy

A complete understanding of blood-biomaterial interactions is necessary for the development of blood-compatible biomaterials that can be used for making long-term implants. To this end, in this in vitro study, the interactions of purified blood components with model biomaterials have been studied with an objective of establishing relationships between the surface properties and the biological response. The principal technique that was used in this study is atomic force microscopy (AFM), which allows both visualization of biomolecules in physiologically relevant environments and the measurement of interaction forces from the µN to pN range.

Agnihotri, Aashiish

Pennsylvania State University

2005

2007-08-01

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