Surface Enhanced Raman Spectroscopy (SERS) Substrates

Raman signal intensity can be greatly enhanced when probing organic or biological molecules on substrates decorated with metallic nanostructures. Below are users' publications that report using our plasma instruments to fabricate SERS substrates and to remove probe molecules from SERS substrates without compromising the nanostructure morphology.


  • Tran, Minh, Alison Whale, Sonal Padalkar "Exploring the Efficacy of Platinum and Palladium Nanostructures for Organic Molecule Detection via Raman Spectroscopy" Sensors (2018) 18: 147. doi:10.3390/s18010147
  • Yap, Lim Wei, Huaying Chen, Yuan Gao, Karolina Petkovic, Yan Liang, Kae Jye Si, Huanting Wang, Zhiyong Tang, Yonggang Zhu, Wenlong Cheng "Bifunctional plasmonic-magnetic particles for an enhanced microfluidic SERS immunoassay" Nanoscale (2017) 9: 7822-7829. doi:10.1039/C7NR01511A
  • Ahn, Hyo-Jin, Pradheep Thiyagarajan, Lin Jia, Sun-I Kim, Jong-Chul Yoon, Edwin L. Thomas, Ji-Hyun Jang "An optimal substrate design for SERS: dual-scale diamond-shaped gold nano-structures fabricated via interference lithography" Nanoscale (2013) 5: 1836-1842. doi:10.1039/c3nr33498h
  • Paquet-Mercier, Francois, Nahid Aznaveh, Muhammad Safdar, Jesse Greener "A Microfluidic Bioreactor with in Situ SERS Imaging for the Study of Controlled Flow Patterns of Biofilm Precursor Materials" Sensors (2013) 13: 14714-14727. doi:10.3390/s131114714
  • Cathcart, Nicole, Vladimir Kitaev "Multifaceted prismatic silver nanoparticles: synthesis by chloride-directed selective growth from thiolate-protected clusters and SERS properties" Nanoscale (2012) 4: 6981-6989. doi:10.1039/c2nr32031b
  • Correia-Ledo, D., K.F. Gibson, A. Dhawan, M. Couture, T. Vo-Dinh, D. Graham, J.-F. Masson "Assessing the Location of Surface Plasmons Over Nanotriangle and Nanohole Arrays of Different Size and Periodicity" J. Phys. Chem. C (2012) 116 (12): 6884-6892. doi:10.1021/jp3009018
  • Lu, G, H. Li, S. Wu, P. Chen, H. Zhang "High-density metallic nanogaps fabricated on solid substrates used for surface enhanced Raman scattering" Nanoscale (2012) 4 (3): 860-863. doi:10.1039/c1nr10997a
  • Cathcart, N., V. Kitaev "Monodisperse Hexagonal Silver Nanoprisms: Synthesis via Thiolate-Protected Cluster Precursors and Chiral, Ligand-Imprinted Self-Assembly" ACS Nano (2011) 5 (9): 7411-7425. doi:10.1021/nn2023478
  • Kawaguchi, Kazuhiro, Masahiro Saito, Katsumi Takahiro, Shunya Yamamoto, Masahito Yoshikawa "Blueshift and narrowing of localized surface plasmon resonance of silver nanoparticles exposed to plasma" Plasmonics (2011) 6: 535-539. doi:10.1007/s11468-011-9233-4
  • Negri, P., N. E. Marotta, L. A. Bottomley, R. A. Dluhy "Removal of surface contamination and self-assembled monolayers (SAMS) from silver (Ag) nanorod substrates by plasma cleaning with argon" Appl. Spectrosc. (2011) 65: 66-74. doi:10.1366/10-06037
  • Masson, J.-F., K.F. Gibson, A. Provencher-Girard "Surface-Enhanced Raman Spectroscopy Amplification with Film over Etched Nanospheres" The Journal of Physical Chemistry C (2010) 114 (51): 22406-22412. doi:10.1021/jp106450y
  • Camargo, P. H. C., C. M. Cobley, M. Rycenga, Y. Xia "Measuring the surface-enhanced Raman scattering enhancement factors of hot spots formed between an individual Ag nanowire and a single Ag nanocube" Nanotechnology (2009) 20: 434020. doi:10.1088/0957-4484/20/43/434020
  • Camargo, P.H.C., M. Rycenga, L. Au, Y. Xia "Isolating and Probing the Hot Spot Formed between Two Silver Nanocubes" Angew. Chem., Int. Ed. (2009) 48(12): 2180-2184. doi:10.1002/anie.200806139
  • Kinnan, Mark K., Amar Kumbhar, George Chumanov "Plasma reduction of silver compounds for fabrication of surface-enhanced raman scattering substrates" Appl. Spectrosc. (2008) 62: 721-726. doi:10.1366/000370208784909463
  • Muniz-Miranda, M., B. Pergolese, A. Bigotto, A. Giusti "Stable and efficient silver substrates for SERS spectroscopy" J. Colloid Interface Sci. (2007) 314(2): 540-544. doi:10.1016/j.jcis.2007.05.089
  • Carron, Keith, Ken Mullen, Mark Lanouette, Helena Angersbach "Selective-Ultratrace Detection of Metal Ions with SERS" Appl. Spectrosc. (1991) 45(3): 420-423. doi:10.1366/0003702914337100