HARRICK PLASMA

DNA Compaction onto Hydrophobic Surfaces by Different Cationic Surfactants

DNA compaction by alkyltrimethylammonium surfactants at hydrophobized silica surfaces and the effect of the counterion, as well as the hydrocarbon chain length,wasinvestigated by in situ null-ellipsometry. In addition, DNA compaction in the presence of a gemini surfactant, hexyl-α,ω-bis(dodecyldimethylammonium bromide), was studied. The type of cationic amphiphile used was found not to have a pronounced effect on the mixedDNA-cationic surfactant adsorbed layer thickness, although the surface concentration excess for the mixed layers seemed to follow the same trend as that for DNA-free surfactant layers. Interestingly, it was also found that the stability of the mixed adsorbed layer largely depends on the cationic surfactant used.

Cárdenas, Marité, Tommy Nylander, R. K. Thomas, Björn Lindman

Langmuir

21

6495-6502

2007-03-01

2005

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