HARRICK PLASMA

A new USP Class VI-compliant substrate for manufacturing disposable microfluidic devices

As microfluidic systems transition from research tools to disposable clinical-diagnostic devices, new substrate materials are needed to meet both the regulatory requirement as well as the economics of disposable devices. This paper introduces a UV-curable polyurethane-methacrylate (PUMA) substrate that has been qualified for medical use and meets all of the challenges of manufacturing microfluidic devices. PUMA is optically transparent, biocompatible, and exhibits high electroosmotic mobility without surface modification. We report two production processes that are compatible with the existing methods of rapid prototyping and present characterizations of the resultant PUMA microfluidic devices.

Kuo, J. S., L. Ng, G. S. Yen, R. M. Lorenz, P. G. Schiro, J. S. Edgar, Y. Zhao, D. S. W. Lim, P. B. Allen, G. D. M. Jeffries

Lab Chip

9(7)

870-876

0000-00-00

2009

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